orthokeratinized odontogenic cyst

A clinicopathological and immunocytochemical study of 15 cases These findings suggest that OOC is clinicopathologically separate from other types of odontogenic cysts and may thus constitute a distinct clinical entity. OOC should be histopathologically differentiated from OKC which has a higher recurrence rate and lower mali.


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The treatment of OOC is by enucleation and the prognosis following enucleation is excellent with a.

. There are subtle histological differences between OOC and OKC which confirms the diagnosis. And present rare but significant manifestations of OOC. However studies have shown that OOC has peculiar clinicopathologic aspects when compared with other developmental odontogenic cysts.

Orthokeratinized odontogenic cyst OOC is a developmental cyst of jaw and was initially considered by the World Health Organization 1992 as the uncommon orthokeratinized variant of odontogenic keratocyst OKC. Orthokeratinized odontogenic cyst OOC is an uncommon odontogenic cyst. In 2005 it was classified as a distinct entity.

Orthokeratinized odontogenic cyst OOC is a relatively uncommon developmental cyst of the jaw constituting about 10. OOC had been previously coded as odontogenic keratocyst OKC and was termed as orthokeratinized variant of OKC. Orthokeratinized odontogenic cyst OOC is an odontogenic cyst was initially termed as the uncommon orthokeratinized type of odontogenic keratocyst by the World Health Organization.

Compared with KCOTs expression level of Ki-67 and p63 was significantly lower in OOCs suggesting a lower proliferative activity. It usually occurs in mandible. Twenty-seven of the 54 cysts were associated with an impacted tooth.

The orthokeratinized odontogenic cyst OOC 1 was first clearly identified as an orthokeratinzed variant of the odontogenic keratocyst by Wright in 1981 2 owing to its different histopathology and reduced likelihood to recur. Orthokeratinized odontogenic cyst OOC a newly designated entity of odontogenic cysts is an intraosseous jaw cyst that is entirely or predominantly lined by orthokeratinized squamous epithelium. Orthokeratinized odontogenic cyst OOC is a developmental cyst of jaw and was initially considered by the World Health Organization 1992 as the uncommon orthokeratinized variant of odontogenic keratocyst OKC.

Orthokeratinized odontogenic cyst OOC is a rare type of odontogenic cyst which shows an orthokeratinized stratified squamous epithelium. However there had been controversy because the. However studies have shown that OOC has peculiar clinicopathologic aspects when compared with other developmental odontogenic cysts.

Determine the characteristics of multiple OOCs. Although both the first two editions of the World Health Organizations WHO histological classification of odontogenic tumours. The orthokeratinized odontogenic cyst OOC is a rare developmental odontogenic cyst that has been considered as a variant of the keratocystic odontogenic tumour KCOT until Wright 1981 defined it as a different entity.

Orthokeratinized odontogenic cyst OOC is a pathologic entity that was once described as an uncommon variation of odontogenic keratocyst although the 2005 World Health Organization classification considers this as distinct pathologic entity due to its diverse biological behaviors. The objective of this study was to demonstrate the clinical radiologic and histologic features of orthokeratinized odontogenic cyst OOC. The aim of this study was to report a large series of OOC to substantiate its clinicopathologic profiles and to investigate PTCH1 mutations in OOCs.

Surgery is the usual treatment and recurrence or association with Gorlin-Goltz syndrome has rarely been described. Orthokeratinized odontogenic cyst OOC is a rare developmental odontogenic cyst characterized by orthokeratinized stratified squamous epithelial lining. Recognition of OOC as a unique entity is of utmost importance as it bears.

Orthokeratinized Odontogenic Cyst OOC is a rare developmental odontogenic cyst which was considered in the past to be a variant of Odontogenic keratocyst OKC later renamed as keratocystic odontogenic tumor KCOT. Various studies have shown that OOC has typical characteristic clinicopathologic features when compared to other developmental. It has been categorized as a subtype of odontogenic keratocyst OKC.

Follow-up of 42 patients revealed no recurrence during an average period of 768 months after surgery. A clinical radiologic and histopathologic study of 65 primary and 2 recurrent OOC cases was performed. It was originally considered as a type of odontogenic keratocyst OKC but later identified as separate entity.


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